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Adapting Yeast as Model to Study Ricin Toxin A Uptake and Trafficking(‡)

The plant A/B toxin ricin represents a heterodimeric glycoprotein belonging to the family of ribosome inactivating proteins, RIPs. Its toxicity towards eukaryotic cells results from the depurination of 28S rRNA due to the N-glycosidic activity of ricin toxin A chain, RTA. Since the extention of RTA...

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Detalhes bibliográficos
Main Authors: Becker, Björn, Schmitt, Manfred J.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3202858/
https://ncbi.nlm.nih.gov/pubmed/22069743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins3070834
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