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Yeast Reporter Assay to Identify Cellular Components of Ricin Toxin A Chain Trafficking

RTA, the catalytic A-subunit of the ribosome inactivating A/B toxin ricin, inhibits eukaryotic protein biosynthesis by depurination of 28S rRNA. Although cell surface binding of ricin holotoxin is mainly mediated through its B-subunit (RTB), sole application of RTA is also toxic, albeit to a signifi...

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Detalhes bibliográficos
Publicado no:Toxins (Basel)
Main Authors: Becker, Björn, Schnöder, Tina, Schmitt, Manfred J.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5198560/
https://ncbi.nlm.nih.gov/pubmed/27929418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins8120366
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