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Yeast Reporter Assay to Identify Cellular Components of Ricin Toxin A Chain Trafficking
RTA, the catalytic A-subunit of the ribosome inactivating A/B toxin ricin, inhibits eukaryotic protein biosynthesis by depurination of 28S rRNA. Although cell surface binding of ricin holotoxin is mainly mediated through its B-subunit (RTB), sole application of RTA is also toxic, albeit to a signifi...
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| Udgivet i: | Toxins (Basel) |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
MDPI
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5198560/ https://ncbi.nlm.nih.gov/pubmed/27929418 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins8120366 |
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