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A yeast killer toxin screen provides insights into A/B toxin entry, trafficking and killing mechanisms

Like Ricin, Shiga, and Cholera toxins, yeast K28 is an A/B toxin that depends on endocytosis and retrograde trafficking for toxicity. Knowledge of the specific proteins, lipids, and mechanisms required for trafficking and killing by these toxins remains incomplete. Since K28 is a model for clinicall...

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Detalhes bibliográficos
Main Authors: Carroll, Susheela Y., Stirling, Peter C., Stimpson, Helen E. M., Gießelmann, Esther, Schmitt, Manfred J., Drubin, David G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2768656/
https://ncbi.nlm.nih.gov/pubmed/19853568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2009.08.006
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