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Production of fluorescent and cytotoxic K28 killer toxin variants through high cell density fermentation of recombinant Pichia pastoris

BACKGROUND: Virus infected killer strains of the baker’s yeast Saccharomyces cerevisiae secrete protein toxins such as K28, K1, K2 and Klus which are lethal to sensitive yeast strains of the same or related species. K28 is somewhat unique as it represents an α/β heterodimeric protein of the A/B toxi...

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Pubblicato in:Microb Cell Fact
Autori principali: Giesselmann, Esther, Becker, Björn, Schmitt, Manfred J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5735513/
https://ncbi.nlm.nih.gov/pubmed/29258515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-017-0844-0
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