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Production of fluorescent and cytotoxic K28 killer toxin variants through high cell density fermentation of recombinant Pichia pastoris

BACKGROUND: Virus infected killer strains of the baker’s yeast Saccharomyces cerevisiae secrete protein toxins such as K28, K1, K2 and Klus which are lethal to sensitive yeast strains of the same or related species. K28 is somewhat unique as it represents an α/β heterodimeric protein of the A/B toxi...

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Détails bibliographiques
Publié dans:Microb Cell Fact
Auteurs principaux: Giesselmann, Esther, Becker, Björn, Schmitt, Manfred J.
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5735513/
https://ncbi.nlm.nih.gov/pubmed/29258515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-017-0844-0
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