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Gene Network Signaling in Hormone Responsiveness Modifies Apoptosis and Autophagy in Breast Cancer Cells

Resistance to endocrine therapies, whether de novo or acquired, remains a major limitation in the ability to cure many tumors that express detectable levels of the estrogen receptor alpha protein (ER). While several resistance phenotypes have been described, endocrine unresponsiveness in the context...

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Detalhes bibliográficos
Main Authors: Clarke, Robert, Shajahan, Ayesha N., Riggins, Rebecca B., Cho, Younsook, Crawford, Anatasha, Xuan, Jianhua, Wang, Yue, Zwart, Alan, Nehra, Ruchi, Liu, Minetta C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2768542/
https://ncbi.nlm.nih.gov/pubmed/19444933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsbmb.2008.12.023
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