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Glucose-Regulated Protein 78 Controls Cross-talk between Apoptosis and Autophagy to Determine Antiestrogen Responsiveness

While more than 70% of breast cancers express estrogen receptor-α (ER+), endocrine therapies targeting these receptors often fail. The molecular mechanisms that underlie treatment resistance remain unclear. We investigated the potential role of glucose-regulated protein 78 (GRP78) in mediating estro...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Cook, Katherine L., Shajahan, Ayesha N., Wärri, Anni, Jin, Lu, Hilakivi-Clarke, Leena A., Clarke, Robert
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3576872/
https://ncbi.nlm.nih.gov/pubmed/22752300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-0269
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