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Factor H and Neisserial pathogenesis
Both Neisseria gonorrhoeae and N. meningitidis bind to factor H which enhances their ability to evade complement dependent killing. While porin is the ligand for human fH on gonococci, meningococci use a lipoprotein called factor H binding protein (fHbp) to bind to factor H and enhance their ability...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2008
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2768413/ https://ncbi.nlm.nih.gov/pubmed/19388163 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2008.11.060 |
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