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Role of Gonococcal Neisserial Surface Protein A (NspA) in Serum Resistance and Comparison of Its Factor H Binding Properties with Those of Its Meningococcal Counterpart

Neisseria gonorrhoeae, the causative agent of gonorrhea, has evolved several mechanisms to subvert complement, including binding of the complement inhibitor factor H (FH). We previously reported FH binding to N. gonorrhoeae independently of lipooligosaccharide (LOS) sialylation. Here we report that...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Lewis, Lisa A., Rice, Peter A., Ram, Sanjay
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6346132/
https://ncbi.nlm.nih.gov/pubmed/30510105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00658-18
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