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Inhibition of Src family kinases with dasatinib blocks migration and invasion of human melanoma cells

Src family kinases (SFKs) are involved in regulating a multitude of biological processes including cell adhesion, migration, proliferation and survival, depending on the cellular context. Therefore, although SFKs are currently being investigated as potential targets for treatment strategies in vario...

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Hlavní autoři: Buettner, Ralf, Mesa, Tania, Vultur, Adina, Lee, Frank, Jove, Richard
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2768340/
https://ncbi.nlm.nih.gov/pubmed/19010823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-08-0169
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