A carregar...
Challenging a Paradigm: Theoretical Calculations of the Protonation State of the Cys25-His159 Catalytic Diad in Free Papain
A central mechanistic paradigm of cysteine proteases is that the His – Cys catalytic diad forms an ion-pair NH(+)/S(−) already in the catalytically active free enzyme. Most molecular modeling studies of cysteine proteases refer to this paradigm as their starting point. Nevertheless, several recent k...
Na minha lista:
| Main Authors: | , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2767454/ https://ncbi.nlm.nih.gov/pubmed/19688822 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.22516 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|