Structure/Function Relationships of Adipose Phospholipase A(2) Containing a Cys-His-His Catalytic Triad

Adipose phospholipase A(2) (AdPLA or Group XVI PLA(2)) plays an important role in the onset of obesity by suppressing adipose tissue lipolysis. As a consequence, AdPLA-deficient mice are resistant to obesity induced by a high fat diet or leptin deficiency. It has been proposed that AdPLA mediates it...

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Bibliografiske detaljer
Main Authors: Pang, Xiao-Yan, Cao, Jian, Addington, Linsee, Lovell, Scott, Battaile, Kevin P., Zhang, Na, Rao, J. L. Uma Maheswar, Dennis, Edward A., Moise, Alexander R.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2012
Fag:
Enzymology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3471684/
https://ncbi.nlm.nih.gov/pubmed/22923616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.398859
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