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Structural analysis of a Vibrio phospholipase reveals an unusual Ser–His–chloride catalytic triad
Phospholipases can disrupt host membranes and are important virulence factors in many pathogens. VvPlpA is a phospholipase A(2) secreted by Vibrio vulnificus and essential for virulence. Its homologs, termed thermolabile hemolysins (TLHs), are widely distributed in Vibrio bacteria, but no structural...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6663882/ https://ncbi.nlm.nih.gov/pubmed/31073025 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.008280 |
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