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GITR signaling potentiates airway hyperresponsiveness by enhancing Th2 cell activity in a mouse model of asthma
BACKGROUND: Allergic asthma is characterized by airway hyperresponsiveness (AHR) and allergic inflammation of the airways, driven by allergen-specific Th2 cells. The asthma phenotypes and especially AHR are sensitive to the presence and activity of regulatory T (Treg) cells in the lung. Glucocortico...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BioMed Central
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2767348/ https://ncbi.nlm.nih.gov/pubmed/19811658 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-10-93 |
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