GITR signaling potentiates airway hyperresponsiveness by enhancing Th2 cell activity in a mouse model of asthma

BACKGROUND: Allergic asthma is characterized by airway hyperresponsiveness (AHR) and allergic inflammation of the airways, driven by allergen-specific Th2 cells. The asthma phenotypes and especially AHR are sensitive to the presence and activity of regulatory T (Treg) cells in the lung. Glucocortico...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Motta, Alexandre C, Vissers, Joost LM, Gras, Renée, Van Esch, Betty CAM, Van Oosterhout, Antoon JM, Nawijn, Martijn C
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2009
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2767348/
https://ncbi.nlm.nih.gov/pubmed/19811658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-10-93
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker