Investigation of the mechanism of action of alemtuzumab in a human CD52 transgenic mouse model

Alemtuzumab is a humanized monoclonal antibody against CD52, an antigen found on the surface of normal and malignant lymphocytes. It is approved for the treatment of B-cell chronic lymphocytic leukaemia and is undergoing Phase III clinical trials for the treatment of multiple sclerosis. The exact me...

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Detaylı Bibliyografya
Asıl Yazarlar: Hu, Yanping, Turner, Michael J, Shields, Jacqueline, Gale, Matthew S, Hutto, Elizabeth, Roberts, Bruce L, Siders, William M, Kaplan, Johanne M
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Blackwell Science Inc 2009
Konular:
Original Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2767316/
https://ncbi.nlm.nih.gov/pubmed/19740383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2009.03115.x
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