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Impact of alemtuzumab treatment on the survival and function of human regulatory T cells in vitro

Alemtuzumab is a humanized monoclonal antibody specific for the CD52 protein present at high levels on the surface of B and T lymphocytes. In clinical trials, alemtuzumab has shown a clinical benefit superior to that of interferon-β in relapsing–remitting multiple sclerosis patients. Treatment with...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Havari, Evis, Turner, Michael J, Campos-Rivera, Juanita, Shankara, Srinivas, Nguyen, Tri-Hung, Roberts, Bruce, Siders, William, Kaplan, Johanne M
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Science Inc 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3893855/
https://ncbi.nlm.nih.gov/pubmed/24116901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12178
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