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Insights into the Mechanisms of the Therapeutic Efficacy of Alemtuzumab in Multiple Sclerosis

The pathogenesis of multiple sclerosis (MS) is thought to involve peripheral activation of immune cells against central nervous system (CNS) antigens and their migration across the blood–brain barrier, leading to CNS inflammation and neurodegeneration. Alemtuzumab, a humanized anti-CD52 monoclonal a...

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Библиографические подробности
Главные авторы: Freedman, Mark S, Kaplan, Johanne M, Markovic-Plese, Silva
Формат: Artigo
Язык:Inglês
Опубликовано: 2013
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3869402/
https://ncbi.nlm.nih.gov/pubmed/24363961
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