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Investigation of the mechanism of action of alemtuzumab in a human CD52 transgenic mouse model
Alemtuzumab is a humanized monoclonal antibody against CD52, an antigen found on the surface of normal and malignant lymphocytes. It is approved for the treatment of B-cell chronic lymphocytic leukaemia and is undergoing Phase III clinical trials for the treatment of multiple sclerosis. The exact me...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Blackwell Science Inc
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2767316/ https://ncbi.nlm.nih.gov/pubmed/19740383 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2009.03115.x |
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