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Inhibition of β-amyloid(1-40) Peptide Aggregation and Neurotoxicity by Citrate

The accumulation of β-amyloid (Aβ) aggregates is a characteristic of Alzheimer's disease (AD). Furthermore, these aggregates have neurotoxic effects on cells, and thus, molecules that inhibit Aβ aggregate formation could be valuable therapeutics for AD. It is well known that aggregation of Aβ d...

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Autori principali: Park, Yong Hoon, Kim, Young-Jin, Son, Il Hong, Yang, Hyun Duk
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Korean Physiological Society and The Korean Society of Pharmacology 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2766705/
https://ncbi.nlm.nih.gov/pubmed/19885010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4196/kjpp.2009.13.4.273
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