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Dysregulation of human bestrophin-1 by ceramide-induced dephosphorylation

Best vitelliform macular dystrophy is an inherited autosomal dominant, juvenile onset form of macular degeneration caused by mutations in a chloride ion channel, human bestrophin-1 (hBest1). Mutations in Best1 have also been linked to several other forms of retinopathy. In addition to mutations, hBe...

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Autori principali: Xiao, Qinghuan, Yu, Kuai, Cui, Yuan-yuan, Hartzell, H Criss
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2766645/
https://ncbi.nlm.nih.gov/pubmed/19635817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2009.176800
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