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Regulation of Bestrophin Cl Channels by Calcium: Role of the C Terminus

Human bestrophin-1 (hBest1), which is genetically linked to several kinds of retinopathy and macular degeneration in both humans and dogs, is the founding member of a family of Cl(−) ion channels that are activated by intracellular Ca(2+). At present, the structures and mechanisms responsible for Ca...

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Detalhes bibliográficos
Main Authors: Xiao, Qinghuan, Prussia, Andrew, Yu, Kuai, Cui, Yuan-yuan, Hartzell, H. Criss
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2585866/
https://ncbi.nlm.nih.gov/pubmed/19029375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200810056
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