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Bestrophin-2 mediates bicarbonate transport by goblet cells in mouse colon
Anion transport by the colonic mucosa maintains the hydration and pH of the colonic lumen, and its disruption causes a variety of diarrheal diseases. Cholinergic agonists raise cytosolic Ca(2+) levels and stimulate anion secretion, but the mechanisms underlying this effect remain unclear. Cholinergi...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Clinical Investigation
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2860923/ https://ncbi.nlm.nih.gov/pubmed/20407206 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI41129 |
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