Bestrophin-2 mediates bicarbonate transport by goblet cells in mouse colon

Anion transport by the colonic mucosa maintains the hydration and pH of the colonic lumen, and its disruption causes a variety of diarrheal diseases. Cholinergic agonists raise cytosolic Ca(2+) levels and stimulate anion secretion, but the mechanisms underlying this effect remain unclear. Cholinergi...

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Main Authors: Yu, Kuai, Lujan, Rafael, Marmorstein, Alan, Gabriel, Sherif, Hartzell, H. Criss
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2010
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2860923/
https://ncbi.nlm.nih.gov/pubmed/20407206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI41129
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