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The Tyrosine Kinase Csk Dimerizes through Its SH3 Domain

The Src family kinases possess two sites of tyrosine phosphorylation that are critical to the regulation of kinase activity. Autophosphorylation on an activation loop tyrosine residue (Tyr 416 in commonly used chicken c-Src numbering) increases catalytic activity, while phosphorylation of a C-termin...

詳細記述

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書誌詳細
主要な著者: Levinson, Nicholas M., Visperas, Patrick R., Kuriyan, John
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2766628/
https://ncbi.nlm.nih.gov/pubmed/19888460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007683
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