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Theoretical Insights Reveal Novel Motions in Csk's SH3 Domain That Control Kinase Activation.

The Src family of tyrosine kinases (SFKs) regulate numerous aspects of cell growth and differentiation and are under the principal control of the C-terminal Src Kinase (Csk). Although Csk and SFKs share conserved kinase, SH2 and SH3 domains, they differ considerably in three-dimensional structure, r...

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Main Authors: Sulyman Barkho, Levi C T Pierce, Sheng Li, Joseph A Adams, Patricia A Jennings
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science (PLoS) 2015-01-01
סדרה:PLoS ONE
גישה מקוונת:http://europepmc.org/articles/PMC4452171?pdf=render
תגים: הוספת תג
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