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SH2 Domain-Mediated Interaction of Inhibitory Protein Tyrosine Kinase Csk with Protein Tyrosine Phosphatase-HSCF

The protein tyrosine kinase (PTK) Csk is a potent negative regulator of several signal transduction processes, as a consequence of its exquisite ability to inactivate Src-related PTKs. This function requires not only the kinase domain of Csk, but also its Src homology 3 (SH3) and SH2 regions. We sho...

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Autors principals: Wang, Bing, Lemay, Serge, Tsai, Schickwann, Veillette, André
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC99562/
https://ncbi.nlm.nih.gov/pubmed/11158295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.4.1077-1088.2001
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