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The Argonaute CSR-1 and its 22G-RNA co-factors target germline genes and are required for holocentric chromosome segregation
RNAi-related pathways regulate diverse processes, from developmental timing to transposon silencing. Here, we show that in C. elegans the Argonaute CSR-1, the RNA-dependent RNA polymerase EGO-1, the Dicer-related helicase DRH-3, and the Tudor-domain protein EKL-1 localize to chromosomes and are requ...
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| Autori principali: | , , , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2766185/ https://ncbi.nlm.nih.gov/pubmed/19804758 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2009.09.014 |
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