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Experimental determination of the evolvability of a transcription factor
Sequence-specific binding of a transcription factor to DNA is the central event in any transcriptional regulatory network. However, relatively little is known about the evolutionary plasticity of transcription factors. For example, the exact functional consequence of an amino acid substitution on th...
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Auteurs principaux: | , |
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Format: | Artigo |
Langue: | Inglês |
Publié: |
National Academy of Sciences
2009
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2765923/ https://ncbi.nlm.nih.gov/pubmed/19841254 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0907688106 |
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