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An in vitro microfluidic approach to generating protein-interaction networks

We developed an in vitro protein expression and interaction analysis platform based on a highly parallel and sensitive microfluidic affinity assay, and used it for 14,792 on-chip experiments, which exhaustively measured the protein-protein interactions of 43 Streptococcus pneumoniae proteins in quad...

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Detalhes bibliográficos
Main Authors: Gerber, Doron, Maerkl, Sebastian J, Quake, Stephen R
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4117197/
https://ncbi.nlm.nih.gov/pubmed/19098921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.1289
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