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Discovery of a hepatitis C target and its pharmacological inhibitors by microfluidic affinity analysis
More effective therapies are urgently needed against hepatitis C virus (HCV), a major cause of viral hepatitis. We used in vitro protein expression and microfluidic affinity analysis to study RNA binding by the HCV transmembrane protein NS4B, which plays an essential role in HCV RNA replication. We...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4110250/ https://ncbi.nlm.nih.gov/pubmed/18758449 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.1490 |
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