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Experimental strategies for studying transcription factor–DNA binding specificities

Specific binding of transcription factors (TFs) determines in a large part the connectivity of gene regulatory networks as well as the quantitative level of gene expression. A multiplicity of both experimental and computational methods is currently used to discover and characterize the underlying TF...

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Detalhes bibliográficos
Main Authors: Geertz, Marcel, Maerkl, Sebastian J.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3080775/
https://ncbi.nlm.nih.gov/pubmed/20864494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bfgp/elq023
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