Differential recognition of CD1d-α-galactosyl ceramide by the Vβ8.2 and Vβ7 semi-invariant NKT T-cell receptors

CD1d presents lipid-based antigens (Ag) that are recognised by the semi-invariant T cell receptor (TCR) expressed on Natural Killer T (NKT) cells. While the TCR α-chain is typically invariant, the TCR β-chain expression is more diverse, particularly in mice where at least three different Vβ chains a...

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Detalhes bibliográficos
Main Authors: Pellicci, Daniel G., Patel, Onisha, Kjer-Nielsen, Lars, Pang, Siew Siew, Sullivan, Lucy C., Kyparissoudis, Konstantinos, Brooks, Andrew G., Reid, Hugh H., Gras, Stephanie, Lucet, Isabelle, Koh, Ruide, Smyth, Mark J., Mallevaey, Thierry, Matsuda, Jennifer L., Gapin, Laurent, McCluskey, James, Godfrey, Dale I., Rossjohn, Jamie
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2765864/
https://ncbi.nlm.nih.gov/pubmed/19592275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2009.04.018
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