Differential recognition of CD1d-α-galactosyl ceramide by the Vβ8.2 and Vβ7 semi-invariant NKT T-cell receptors

CD1d presents lipid-based antigens (Ag) that are recognised by the semi-invariant T cell receptor (TCR) expressed on Natural Killer T (NKT) cells. While the TCR α-chain is typically invariant, the TCR β-chain expression is more diverse, particularly in mice where at least three different Vβ chains a...

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Hauptverfasser: Pellicci, Daniel G., Patel, Onisha, Kjer-Nielsen, Lars, Pang, Siew Siew, Sullivan, Lucy C., Kyparissoudis, Konstantinos, Brooks, Andrew G., Reid, Hugh H., Gras, Stephanie, Lucet, Isabelle, Koh, Ruide, Smyth, Mark J., Mallevaey, Thierry, Matsuda, Jennifer L., Gapin, Laurent, McCluskey, James, Godfrey, Dale I., Rossjohn, Jamie
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2765864/
https://ncbi.nlm.nih.gov/pubmed/19592275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2009.04.018
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