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EVALUATION OF SILICA MONOLITHS IN AFFINITY MICROCOLUMNS FOR HIGH-THROUGHPUT ANALYSIS OF DRUG-PROTEIN INTERACTIONS

Silica monoliths in affinity microcolumns were tested for the high-throughput analysis of drug-protein interactions. Human serum albumin (HSA) was used as a model protein for this work, while carbamazepine and R-warfarin were used as model analytes. A comparison of HSA silica monoliths of various le...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Yoo, Michelle J., Hage, David S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2765799/
https://ncbi.nlm.nih.gov/pubmed/19630007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jssc.200900346
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