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USE OF PEAK DECAY ANALYSIS AND AFFINITY MICROCOLUMNS CONTAINING SILICA MONOLITHS FOR RAPID DETERMINATION OF DRUG-PROTEIN DISSOCIATION RATES
This report examined the use of silica monoliths in affinity microcolumns containing human serum albumin (HSA) to measure the dissociation rates for various drugs from this protein. Immobilized HSA and control monolith columns with dimensions of 1 mm × 4.6 mm i.d. were prepared for this work and use...
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| Główni autorzy: | , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
2010
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3024456/ https://ncbi.nlm.nih.gov/pubmed/20956006 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chroma.2010.09.070 |
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