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EVALUATION OF AFFINITY MICROCOLUMNS CONTAINING HUMAN SERUM ALBUMIN FOR RAPID ANALYSIS OF DRUG-PROTEIN BINDING
This study examined the use of affinity microcolumns as tools for the rapid analysis and high-throughput screening of drug-protein binding. The protein used was immobilized human serum albumin (HSA) and the model analytes were warfarin and L-tryptophan, two solutes often used as site-specific probes...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2878846/ https://ncbi.nlm.nih.gov/pubmed/20462808 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jchromb.2010.04.028 |
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