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Context-dependent substrate recognition by protein farnesyltransferase

Prenylation is a post-translational modification whereby C-terminal lipidation leads to protein localization to membranes. A C-terminal “Ca(1)a(2)X” sequence has been proposed as the recognition motif for two prenylation enzymes, protein farnesyltransferase (FTase) and protein geranylgeranyltransfer...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Hougland, James L., Lamphear, Corissa L., Scott, Sarah A., Gibbs, Richard A., Fierke, Carol A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2765569/
https://ncbi.nlm.nih.gov/pubmed/19199818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi801710g
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