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Design, Synthesis, and Evaluation of an α-Helix Mimetic Library Targeting Protein-Protein Interactions
-The design and solution-phase synthesis of an α-helix mimetic library as an integral component of a small molecule library targeting protein-protein interactions are described. The iterative design, synthesis, and evaluation of the candidate α-helix mimetic was initiated from a precedented triaryl...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2765553/ https://ncbi.nlm.nih.gov/pubmed/19334711 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja810025g |
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