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Characterization of Two Different 5-Coordinate Soluble Guanylate Cyclase Ferrous Nitrosyl Complexes
Soluble guanylate cyclase (sGC), a hemoprotein, is the primary nitric oxide (NO) receptor in higher eukaryotes. The binding of NO to sGC leads to the formation of a 5-coordinate ferrous-nitrosyl complex, and a several hundred-fold increase in cGMP synthesis. NO activation of sGC is influenced by GTP...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2008
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2765461/ https://ncbi.nlm.nih.gov/pubmed/18302323 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi7022943 |
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