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Conformationally Distinct Five-Coordinate Heme-NO Complexes of Soluble Guanylate Cyclase Elucidated by Multifrequency EPR
Soluble guanylate cyclase (sGC) is a heme-containing enzyme that senses nitric oxide (NO). Formation of a heme Fe-NO complex is essential to sGC activation, and several spectroscopic techniques, including electron paramagnetic resonance (EPR) spectroscopy, have been aimed at elucidating the active e...
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| 出版年: | Biochemistry |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6342452/ https://ncbi.nlm.nih.gov/pubmed/22985445 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi300831m |
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