Phase I trial of temozolomide plus O(6)-benzylguanine 5-day regimen with recurrent malignant glioma

This phase I clinical trial conducted with patients who had recurrent or progressive malignant glioma (MG) was designed to determine the maximum tolerated dose (MTD) and toxicity of three different 5-day dosing regimens of temozolomide (TMZ) in combination with O(6)-benzylguanine (O(6)-BG). Both TMZ...

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Bibliografiske detaljer
Main Authors: Quinn, Jennifer A., Jiang, Sara Xiaoyin, Reardon, David A., Desjardins, Annick, Vredenburgh, James J., Rich, Jeremy N., Gururangan, Sridharan, Friedman, Allan H., Bigner, Darell D., Sampson, John H., McLendon, Roger E., Herndon, James E., Walker, Amy, Friedman, Henry S.
Format: Artigo
Sprog:Inglês
Udgivet: Duke University Press 2009
Fag:
Clinical Investigations
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2765345/
https://ncbi.nlm.nih.gov/pubmed/19289491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1215/15228517-2009-007
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