Protective effects of mildronate in an experimental model of type 2 diabetes in Goto-Kakizaki rats

BACKGROUND AND PURPOSE: Mildronate [3-(2,2,2-trimethylhydrazinium) propionate] is an anti-ischaemic drug whose mechanism of action is based on its inhibition of L-carnitine biosynthesis and uptake. As L-carnitine plays a pivotal role in the balanced metabolism of fatty acids and carbohydrates, this...

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Главные авторы: Liepinsh, Edgars, Vilskersts, Reinis, Zvejniece, Liga, Svalbe, Baiba, Skapare, Elina, Kuka, Janis, Cirule, Helena, Grinberga, Solveiga, Kalvinsh, Ivars, Dambrova, Maija
Формат: Artigo
Язык:Inglês
Опубликовано: Blackwell Publishing Ltd 2009
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Research Papers
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2765322/
https://ncbi.nlm.nih.gov/pubmed/19594753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2009.00319.x
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