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Structure and Function of CutC Choline Lyase from Human Microbiota Bacterium Klebsiella pneumoniae
CutC choline trimethylamine-lyase is an anaerobic bacterial glycyl radical enzyme (GRE) that cleaves choline to produce trimethylamine (TMA) and acetaldehyde. In humans, TMA is produced exclusively by the intestinal microbiota, and its metabolite, trimethylamine oxide, has been associated with a hig...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4571895/ https://ncbi.nlm.nih.gov/pubmed/26187464 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.670471 |
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