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Excretion of the Polymyxin Derivative NAB739 in Murine Urine

Extremely multiresistant strains of Enterobacteriaceae are emerging and spreading at a worrisome pace. Polymyxins are used as the last-resort therapy against such strains, in spite of their nephrotoxicity. We have previously shown that novel polymyxin derivatives NAB739 and NAB815 are less nephrotox...

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Detalhes bibliográficos
Publicado no:Antibiotics (Basel)
Main Authors: Vaara, Martti, Vaara, Timo, Kuka, Janis, Sevostjanovs, Eduards, Grinberga, Solveiga, Dambrova, Maija, Liepinsh, Edgars
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7235871/
https://ncbi.nlm.nih.gov/pubmed/32230751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antibiotics9040143
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