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Chromatographic benefits of elevated temperature for the proteomic analysis of membrane proteins

Integral membrane proteins (IMPs) perform crucial cellular functions and are the primary targets for most pharmaceutical agents. However, the hydrophobic nature of their membrane-embedded domains and their intimate association with lipids makes them difficult to handle. Multiple proteomics platforms...

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Detalhes bibliográficos
Main Authors: Blackler, Adele R., Speers, Anna E., Wu, Christine C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2765112/
https://ncbi.nlm.nih.gov/pubmed/18780350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pmic.200800210
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