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A Shotgun Proteomic Method for the Identification of Membrane-Embedded Proteins and Peptides

Integral membrane proteins perform crucial cellular functions and are the targets for the majority of pharmaceutical agents. However, the hydrophobic nature of their membrane-embedded domains makes them difficult to work with. Here, we describe a shotgun proteomic method for the high-throughput anal...

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Detalhes bibliográficos
Main Authors: Blackler, Adele R., Speers, Anna E., Ladinsky, Mark S., Wu, Christine C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2765231/
https://ncbi.nlm.nih.gov/pubmed/18537282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/pr700795f
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