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Chromatographic benefits of elevated temperature for the proteomic analysis of membrane proteins

Integral membrane proteins (IMPs) perform crucial cellular functions and are the primary targets for most pharmaceutical agents. However, the hydrophobic nature of their membrane-embedded domains and their intimate association with lipids makes them difficult to handle. Multiple proteomics platforms...

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Bibliografske podrobnosti
Main Authors: Blackler, Adele R., Speers, Anna E., Wu, Christine C.
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2765112/
https://ncbi.nlm.nih.gov/pubmed/18780350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pmic.200800210
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