Thrombospondin-1 is a critical effector of oncosuppressive activity of sst2 somatostatin receptor on pancreatic cancer

The somatostatin receptor subtype 2 (sst2) behaves as a tumor suppressor when expressed and stimulated by its ligand somatostatin in pancreatic cancer. We reveal a mechanism underlying oncosuppressive action of sst2, whereby this inhibitory receptor upregulates the expression of the secreted angioin...

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Detalhes bibliográficos
Main Authors: Laklai, Hanane, Laval, Séverine, Dumartin, Laurent, Rochaix, Philippe, Hagedorn, Martin, Bikfalvi, Andreas, Le Guellec, Sophie, Delisle, Marie-Bernadette, Schally, Andrew V., Susini, Christiane, Pyronnet, Stéphane, Bousquet, Corinne
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2764925/
https://ncbi.nlm.nih.gov/pubmed/19805200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0908674106
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