Somatostatin receptor subtype 2 sensitizes human pancreatic cancer cells to death ligand-induced apoptosis

Somatostatin receptor subtype 2 (sst2) gene expression is lost in 90% of human pancreatic adenocarcinomas. We previously demonstrated that stable sst2 transfection of human pancreatic BxPC-3 cells, which do not endogenously express sst2, inhibits cell proliferation, tumorigenicity, and metastasis. T...

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Détails bibliographiques
Auteurs principaux: Guillermet, Julie, Saint-Laurent, Nathalie, Rochaix, Philippe, Cuvillier, Olivier, Levade, Thierry, Schally, Andrew V., Pradayrol, Lucien, Buscail, Louis, Susini, Christiane, Bousquet, Corinne
Format: Artigo
Langue:Inglês
Publié: The National Academy of Sciences 2003
Sujets:
Biological Sciences
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC140912/
https://ncbi.nlm.nih.gov/pubmed/12490654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0136771100
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