Inhibition of growth and metastatic progression of pancreatic carcinoma in hamster after somatostatin receptor subtype 2 (sst2) gene expression and administration of cytotoxic somatostatin analog AN-238

The sst2 somatostatin receptor mediates the antiproliferative effects of somatostatin analogs. The present study demonstrates that stable expression of sst2 in the hamster pancreatic cancer cells PC-1 and PC-1.0 activates an autocrine negative loop leading to an in vitro inhibition of cell prolifera...

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Detalhes bibliográficos
Main Authors: Benali, Naoual, Cordelier, Pierre, Calise, Denis, Pagès, Philippe, Rochaix, Philippe, Nagy, Attila, Estève, Jean-Pierre, Pour, Parviz M., Schally, Andrew V., Vaysse, Nicole, Susini, Christiane, Buscail, Louis
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2000
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC16842/
https://ncbi.nlm.nih.gov/pubmed/10900262
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